Gene description for Aqp1
Gene name	aquaporin 1
Gene symbol	Aqp1
Other names/aliases	CHIP28
Species	Rattus norvegicus
Database cross references - Aqp1
ExoCarta	ExoCarta_25240
Vesiclepedia	VP_25240
Entrez Gene	25240
UniProt	P29975
Aqp1 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Urine	20535238

Gene ontology annotations for Aqp1

Molecular Function     intracellularly cGMP-activated cation channel activity GO:0005223 ISO     intracellularly cGMP-activated cation channel activity GO:0005223 ISS     potassium channel activity GO:0005267 ISO     potassium channel activity GO:0005267 ISS     water transmembrane transporter activity GO:0005372 ISO     protein binding GO:0005515 IPI     ammonium channel activity GO:0008519 IBA     ammonium channel activity GO:0008519 ISO     ammonium channel activity GO:0008519 ISS     potassium ion transmembrane transporter activity GO:0015079 ISO     glycerol transmembrane transporter activity GO:0015168 IBA     glycerol transmembrane transporter activity GO:0015168 IDA     glycerol transmembrane transporter activity GO:0015168 ISO     water channel activity GO:0015250 IBA     water channel activity GO:0015250 IMP     water channel activity GO:0015250 ISO     water channel activity GO:0015250 ISS     transmembrane transporter activity GO:0022857 ISO     nitric oxide transmembrane transporter activity GO:0030184 ISO     nitric oxide transmembrane transporter activity GO:0030184 ISS     carbon dioxide transmembrane transporter activity GO:0035379 IBA     carbon dioxide transmembrane transporter activity GO:0035379 ISO     carbon dioxide transmembrane transporter activity GO:0035379 ISS     identical protein binding GO:0042802 ISO     ephrin receptor binding GO:0046875 ISO     hydrogen peroxide channel activity GO:0140070 ISO Biological Process     glomerular filtration GO:0003094 ISO     renal water transport GO:0003097 IBA     renal water transport GO:0003097 ISO     renal water transport GO:0003097 ISS     potassium ion transport GO:0006813 ISO     water transport GO:0006833 IMP     water transport GO:0006833 ISO     water transport GO:0006833 ISO     cell volume homeostasis GO:0006884 ISO     cell volume homeostasis GO:0006884 ISS     hyperosmotic response GO:0006972 IBA     hyperosmotic response GO:0006972 IEP     response to hormone GO:0009725 IEP     intracellular water homeostasis GO:0009992 ISO     intracellular water homeostasis GO:0009992 ISS     positive regulation of lamellipodium assembly GO:0010592 IMP     positive regulation of epithelial cell migration GO:0010634 IMP     fibroblast migration GO:0010761 ISO     positive regulation of fibroblast migration GO:0010763 ISO     carbon dioxide transport GO:0015670 ISO     carbon dioxide transport GO:0015670 ISS     glycerol transmembrane transport GO:0015793 IDA     glycerol transmembrane transport GO:0015793 ISO     cell migration GO:0016477 ISO     sensory perception of pain GO:0019233 ISO     cellular homeostasis GO:0019725 ISO     cellular homeostasis GO:0019725 ISS     cGMP-mediated signaling GO:0019934 ISO     cGMP-mediated signaling GO:0019934 ISS     lateral ventricle development GO:0021670 IEP     lateral ventricle development GO:0021670 ISO     pancreatic juice secretion GO:0030157 ISO     nitric oxide transport GO:0030185 ISO     nitric oxide transport GO:0030185 ISS     establishment or maintenance of actin cytoskeleton polarity GO:0030950 ISO     establishment or maintenance of actin cytoskeleton polarity GO:0030950 ISS     secretion by cell GO:0032940 ISO     cerebrospinal fluid secretion GO:0033326 ISO     secretory granule organization GO:0033363 ISO     cellular response to UV GO:0034644 ISO     cellular response to UV GO:0034644 ISS     transepithelial water transport GO:0035377 ISO     transepithelial water transport GO:0035377 ISS     carbon dioxide transmembrane transport GO:0035378 IBA     carbon dioxide transmembrane transport GO:0035378 ISO     carbon dioxide transmembrane transport GO:0035378 ISS     wound healing GO:0042060 ISO     odontogenesis GO:0042476 ISO     negative regulation of apoptotic process GO:0043066 ISO     negative regulation of apoptotic process GO:0043066 ISS     response to estrogen GO:0043627 IEP     lipid digestion GO:0044241 ISO     positive regulation of angiogenesis GO:0045766 ISO     positive regulation of angiogenesis GO:0045766 ISS     positive regulation of saliva secretion GO:0046878 ISO     positive regulation of saliva secretion GO:0046878 ISS     positive regulation of fibroblast proliferation GO:0048146 ISO     positive regulation of fibroblast proliferation GO:0048146 ISS     camera-type eye morphogenesis GO:0048593 ISO     defense response to Gram-negative bacterium GO:0050829 ISO     multicellular organismal-level water homeostasis GO:0050891 ISO     multicellular organismal-level water homeostasis GO:0050891 ISO     corticotropin secretion GO:0051458 ISO     establishment of localization in cell GO:0051649 ISO     renal water absorption GO:0070295 ISO     cellular response to hydrogen peroxide GO:0070301 ISO     cellular response to hydrogen peroxide GO:0070301 ISS     cellular response to mechanical stimulus GO:0071260 ISO     cellular response to mechanical stimulus GO:0071260 ISS     cellular response to copper ion GO:0071280 ISO     cellular response to copper ion GO:0071280 ISS     cellular response to mercury ion GO:0071288 ISO     cellular response to mercury ion GO:0071288 ISS     cellular response to retinoic acid GO:0071300 ISO     cellular response to retinoic acid GO:0071300 ISS     cellular response to cAMP GO:0071320 ISO     cellular response to cAMP GO:0071320 ISS     cellular response to hypoxia GO:0071456 ISO     cellular response to hypoxia GO:0071456 ISS     cellular response to salt stress GO:0071472 ISO     cellular response to salt stress GO:0071472 ISS     cellular hyperosmotic response GO:0071474 ISO     cellular hyperosmotic response GO:0071474 ISS     cellular response to dexamethasone stimulus GO:0071549 ISO     cellular response to dexamethasone stimulus GO:0071549 ISS     cellular response to nitric oxide GO:0071732 ISO     potassium ion transmembrane transport GO:0071805 IEA     metanephric descending thin limb development GO:0072220 ISO     metanephric proximal straight tubule development GO:0072230 ISO     metanephric proximal convoluted tubule segment 2 development GO:0072232 ISO     metanephric proximal tubule development GO:0072237 IEP     metanephric glomerulus vasculature development GO:0072239 ISO     ammonium transmembrane transport GO:0072488 ISO     ammonium transmembrane transport GO:0072488 ISS     hydrogen peroxide transmembrane transport GO:0080170 IEA     negative regulation of cysteine-type endopeptidase activity GO:2000117 ISO Subcellular Localization     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISO     caveola GO:0005901 ISO     brush border GO:0005903 IDA     brush border GO:0005903 ISO     basal plasma membrane GO:0009925 ISO     basal plasma membrane GO:0009925 ISS     membrane GO:0016020 ISO     basolateral plasma membrane GO:0016323 IDA     basolateral plasma membrane GO:0016323 ISO     apical plasma membrane GO:0016324 IDA     apical plasma membrane GO:0016324 ISO     axon GO:0030424 ISO     brush border membrane GO:0031526 ISO     brush border membrane GO:0031526 ISS     nuclear membrane GO:0031965 ISO     nuclear membrane GO:0031965 ISS     neuronal cell body membrane GO:0032809 IDA     sarcolemma GO:0042383 ISO     sarcolemma GO:0042383 ISS     axon terminus GO:0043679 IDA     apical part of cell GO:0045177 ISO     extracellular exosome GO:0070062 ISO     ankyrin-1 complex GO:0170014 ISO     ankyrin-1 complex GO:0170014 ISS