Gene description for DIP2
Gene name DISCO Interacting Protein 2
Gene symbol DIP2
Other names/aliases CG7020
Ddip2
DmelCG7020
Species Drosophila melanogaster
 Database cross references - DIP2
ExoCarta ExoCarta_252479
Entrez Gene 252479
UniProt Q9W0S9  
 DIP2 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for DIP2
Molecular Function
    protein binding GO:0005515 IPI
    transcription factor binding GO:0008134 IEA
    catalytic activity GO:0003824 IEA
Biological Process
    metabolic process GO:0008152 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified DIP2 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DIP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DIP2 is involved
No pathways found





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