Gene description for Gstt1
Gene name glutathione S-transferase theta 1
Gene symbol Gstt1
Other names/aliases GSTYRS
Species Rattus norvegicus
 Database cross references - Gstt1
ExoCarta ExoCarta_25260
Vesiclepedia VP_25260
Entrez Gene 25260
UniProt Q01579  
 Gstt1 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Gstt1
Molecular Function
    glutathione transferase activity GO:0004364 IBA
    glutathione transferase activity GO:0004364 IDA
    glutathione transferase activity GO:0004364 ISO
    glutathione peroxidase activity GO:0004602 IDA
    glutathione peroxidase activity GO:0004602 ISO
    alkylhalidase activity GO:0047651 IDA
Biological Process
    DNA modification GO:0006304 IDA
    glutathione metabolic process GO:0006749 IBA
    glutathione metabolic process GO:0006749 IDA
    glutathione metabolic process GO:0006749 ISO
    glutathione metabolic process GO:0006749 ISO
    response to xenobiotic stimulus GO:0009410 IEP
    response to salicylic acid GO:0009751 IEP
    response to selenium ion GO:0010269 IEP
    response to organic cyclic compound GO:0014070 IEP
    dichloromethane metabolic process GO:0018900 IDA
    response to vitamin E GO:0033197 IEP
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IEA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Gstt1 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Gstt1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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