Gene description for FUT6
Gene name fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
Gene symbol FUT6
Other names/aliases FCT3A
FT1A
Fuc-TVI
FucT-VI
Species Homo sapiens
 Database cross references - FUT6
ExoCarta ExoCarta_2528
Entrez Gene 2528
HGNC 4017
MIM 136836
UniProt P51993  
 FUT6 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for FUT6
Molecular Function
    fucosyltransferase activity GO:0008417 TAS
    3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity GO:0017060 IEA
    alpha-(1->3)-fucosyltransferase activity GO:0046920 TAS
Biological Process
    fucosylation GO:0036065 TAS
    protein glycosylation GO:0006486 TAS
    L-fucose catabolic process GO:0042355 NAS
Subcellular Localization
    Golgi cisterna membrane GO:0032580 IEA
    extracellular exosome GO:0070062 IDA
    Golgi apparatus GO:0005794 TAS
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified FUT6 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for FUT6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FUT6 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here