Gene description for FUT6
Gene name fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
Gene symbol FUT6
Other names/aliases FCT3A
FT1A
Fuc-TVI
FucT-VI
Species Homo sapiens
 Database cross references - FUT6
ExoCarta ExoCarta_2528
Vesiclepedia VP_2528
Entrez Gene 2528
HGNC 4017
MIM 136836
UniProt P51993  
 FUT6 identified in sEVs derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for FUT6
Molecular Function
    fucosyltransferase activity GO:0008417 IDA
    4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity GO:0017083 IDA
    alpha-(1->3)-fucosyltransferase activity GO:0046920 TAS
Biological Process
    protein glycosylation GO:0006486 TAS
    protein N-linked glycosylation GO:0006487 IDA
    protein O-linked glycosylation GO:0006493 IDA
    ceramide metabolic process GO:0006672 IDA
    glycosphingolipid biosynthetic process GO:0006688 IDA
    oocyte axis specification GO:0007309 IBA
    oligosaccharide biosynthetic process GO:0009312 TAS
    N-glycan fucosylation GO:0036071 IDA
    L-fucose catabolic process GO:0042355 NAS
Subcellular Localization
    Golgi membrane GO:0000139 TAS
    extracellular region GO:0005576 IDA
    Golgi apparatus GO:0005794 IDA
    Golgi apparatus GO:0005794 TAS
    Golgi cisterna membrane GO:0032580 IEA
    methylosome GO:0034709 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified FUT6 in sEVs
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for FUT6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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