Gene description for Dync1li1
Gene name dynein cytoplasmic 1 light intermediate chain 1
Gene symbol Dync1li1
Other names/aliases Dncli1
Dnclic1
Species Rattus norvegicus
 Database cross references - Dync1li1
ExoCarta ExoCarta_252902
Entrez Gene 252902
UniProt Q9QXU8  
 Dync1li1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Dync1li1
Molecular Function
    microtubule motor activity GO:0003777 IEA
    poly(A) RNA binding GO:0044822 ISO
    ATP binding GO:0005524 IEA
Biological Process
    metabolic process GO:0008152 IEA
    mitotic spindle organization GO:0007052 TAS
    cell division GO:0051301 IEA
    transport GO:0006810 IEA
    regulation of centrosome cycle GO:0046605 IDA
    microtubule-based movement GO:0007018 IEA
    positive regulation of mitotic cell cycle spindle assembly checkpoint GO:0090267 ISS
Subcellular Localization
    membrane GO:0016020 ISO
    kinetochore GO:0000776 ISS
    condensed chromosome kinetochore GO:0000777 IEA
    centrosome GO:0005813 ISO
    microtubule GO:0005874 IEA
    spindle pole GO:0000922 ISS
    cytoplasm GO:0005737 ISO
    cytoplasmic dynein complex GO:0005868 ISS
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Dync1li1 in exosomes
1
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Dync1li1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dync1li1 is involved
No pathways found





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