Gene description for Slc2a2
Gene name solute carrier family 2 (facilitated glucose transporter), member 2
Gene symbol Slc2a2
Other names/aliases GTT2
Glut2
Species Rattus norvegicus
 Database cross references - Slc2a2
ExoCarta ExoCarta_25351
Entrez Gene 25351
 Slc2a2 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Slc2a2
Molecular Function
    D-glucose transmembrane transporter activity GO:0055056 ISO
    insulin receptor binding GO:0005158 IPI
    dehydroascorbic acid transporter activity GO:0033300 ISO
    sugar:proton symporter activity GO:0005351 IBA
    glucose transmembrane transporter activity GO:0005355 ISO
Biological Process
    glucose transport GO:0015758 ISO
    fructose transport GO:0015755 IEP
    glucose import GO:0046323 IBA
    response to glucose GO:0009749 IEP
    carbohydrate utilization GO:0009758 IMP
    proton transport GO:0015992 IBA
    dehydroascorbic acid transport GO:0070837 ISO
    response to peptide hormone GO:0043434 IEP
    hexose transmembrane transport GO:0035428 ISO
Subcellular Localization
    brush border GO:0005903 ISO
    cytoplasm GO:0005737 ISO
    integral component of plasma membrane GO:0005887 IBA
    plasma membrane GO:0005886 ISO
    cytosol GO:0005829 IDA
    basolateral plasma membrane GO:0016323 IDA
    brush border membrane GO:0031526 IDA
    endosome GO:0005768 IDA
 Experiment description of studies that identified Slc2a2 in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Slc2a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc2a2 is involved
No pathways found





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