Gene description for Eno3
Gene name enolase 3, beta, muscle
Gene symbol Eno3
Other names/aliases BBE
MSE
Species Rattus norvegicus
 Database cross references - Eno3
ExoCarta ExoCarta_25438
Entrez Gene 25438
UniProt P15429  
 Eno3 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Eno3
Molecular Function
    protein homodimerization activity GO:0042803 IDA
    phosphopyruvate hydratase activity GO:0004634 ISO
    protein heterodimerization activity GO:0046982 IDA
    magnesium ion binding GO:0000287 IEA
Biological Process
    substantia nigra development GO:0021762 ISO
    aging GO:0007568 IEP
    skeletal muscle tissue regeneration GO:0043403 IEP
    response to drug GO:0042493 IEP
    glycolytic process GO:0006096 IEA
Subcellular Localization
    phosphopyruvate hydratase complex GO:0000015 IEA
    plasma membrane GO:0005886 ISO
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 IDA
    extracellular space GO:0005615 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Eno3 in exosomes
1
Experiment ID 99
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [QSTAR]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Eno3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Eno3 is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glycolysis IEA Reactome





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