Gene description for Eno3
Gene name enolase 3, beta, muscle
Gene symbol Eno3
Other names/aliases BBE
Species Rattus norvegicus
 Database cross references - Eno3
ExoCarta ExoCarta_25438
Entrez Gene 25438
UniProt P15429  
 Eno3 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Eno3
Molecular Function
    protein homodimerization activity GO:0042803 IDA
    phosphopyruvate hydratase activity GO:0004634 ISO
    protein heterodimerization activity GO:0046982 IDA
    magnesium ion binding GO:0000287 IEA
Biological Process
    substantia nigra development GO:0021762 ISO
    aging GO:0007568 IEP
    skeletal muscle tissue regeneration GO:0043403 IEP
    response to drug GO:0042493 IEP
    glycolytic process GO:0006096 IEA
Subcellular Localization
    phosphopyruvate hydratase complex GO:0000015 IEA
    plasma membrane GO:0005886 ISO
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 IDA
    extracellular space GO:0005615 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Eno3 in exosomes
Experiment ID 99
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [QSTAR]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 3
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Eno3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Eno3 is involved
Gluconeogenesis IEA Reactome
Glycolysis IEA Reactome

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