Gene description for Gss
Gene name glutathione synthetase
Gene symbol Gss
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gss
ExoCarta ExoCarta_25458
Vesiclepedia VP_25458
Entrez Gene 25458
UniProt P46413  
 Gss identified in sEVs derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Gss
Molecular Function
    magnesium ion binding GO:0000287 IEA
    magnesium ion binding GO:0000287 ISO
    magnesium ion binding GO:0000287 ISS
    glutathione synthase activity GO:0004363 IBA
    glutathione synthase activity GO:0004363 IDA
    glutathione synthase activity GO:0004363 IEA
    glutathione synthase activity GO:0004363 ISO
    ATP binding GO:0005524 IDA
    ATP binding GO:0005524 IEA
    ATP binding GO:0005524 ISO
    ATP binding GO:0005524 ISS
    glycine binding GO:0016594 IDA
    peptide binding GO:0042277 IPI
    identical protein binding GO:0042802 IPI
    identical protein binding GO:0042802 ISO
    protein homodimerization activity GO:0042803 IEA
    protein homodimerization activity GO:0042803 ISO
    protein homodimerization activity GO:0042803 ISS
    glutathione binding GO:0043295 IBA
    glutathione binding GO:0043295 IDA
    glutathione binding GO:0043295 IEA
    glutathione binding GO:0043295 ISO
    glutathione binding GO:0043295 ISS
Biological Process
    glutathione biosynthetic process GO:0006750 IDA
    glutathione biosynthetic process GO:0006750 IEA
    response to xenobiotic stimulus GO:0009410 IEP
    response to nutrient levels GO:0031667 IEP
    response to tumor necrosis factor GO:0034612 IEP
    response to amino acid GO:0043200 IEP
    response to cadmium ion GO:0046686 IEA
    response to cadmium ion GO:0046686 ISO
Subcellular Localization
    cytosol GO:0005829 IBA
 Experiment description of studies that identified Gss in sEVs
1
Experiment ID 192
MISEV standards
CEM
Biophysical techniques
TSG101|HSP70|CD63|CD81|FLOT
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M."
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gss
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here