Gene description for Icam1
Gene name	intercellular adhesion molecule 1
Gene symbol	Icam1
Other names/aliases	CD54 ICAM
Species	Rattus norvegicus
Database cross references - Icam1
ExoCarta	ExoCarta_25464
Entrez Gene	25464
UniProt	Q00238
Icam1 identified in exosomes derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Icam1

Molecular Function     integrin binding GO:0005178 ISO     protein complex binding GO:0032403 IPI Biological Process     adhesion of symbiont to host GO:0044406 ISO     response to ionizing radiation GO:0010212 IEP     cellular response to glucose stimulus GO:0071333 ISO     positive regulation of nitric oxide biosynthetic process GO:0045429 IMP     membrane to membrane docking GO:0022614 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     response to gonadotropin GO:0034698 IEP     response to lipopolysaccharide GO:0032496 IEP     cellular response to alkaloid GO:0071312 IEP     positive regulation of vasoconstriction GO:0045907 IMP     sensory perception of sound GO:0007605 IMP     T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:0002291 ISO     leukocyte cell-cell adhesion GO:0007159 ISO     response to copper ion GO:0046688 IEP     acute inflammatory response to antigenic stimulus GO:0002438 IMP     response to organic cyclic compound GO:0014070 IEP     response to amino acid GO:0043200 IEP     negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 ISO     ovarian follicle development GO:0001541 IEP     positive regulation of GTPase activity GO:0043547 IDA     T cell antigen processing and presentation GO:0002457 ISO     regulation of ruffle assembly GO:1900027 ISO     cellular response to nutrient levels GO:0031669 IEP     cellular response to organic substance GO:0071310 IEP     response to amphetamine GO:0001975 IEP     negative regulation of calcium ion transport GO:0051926 IDA     cellular response to lipopolysaccharide GO:0071222 IEP     positive regulation of NF-kappaB transcription factor activity GO:0051092 IMP     cell adhesion mediated by integrin GO:0033627 ISO     leukocyte migration GO:0050900 TAS     cellular response to interleukin-1 GO:0071347 IEP     cellular response to tumor necrosis factor GO:0071356 IEP     cell aging GO:0007569 IEP     regulation of cell shape GO:0008360 IMP     receptor-mediated virion attachment to host cell GO:0046813 ISO     positive regulation of actin filament polymerization GO:0030838 IDA     single organismal cell-cell adhesion GO:0016337 IMP     negative regulation of endothelial cell apoptotic process GO:2000352 ISO     regulation of cell adhesion GO:0030155 ISO     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IDA     cell adhesion GO:0007155 ISO     response to hypoxia GO:0001666 IEP     response to ethanol GO:0045471 IEP     establishment of Sertoli cell barrier GO:0097368 IDA     establishment of endothelial barrier GO:0061028 ISO     response to drug GO:0042493 IEP     positive regulation of cellular extravasation GO:0002693 ISO     cellular response to hypoxia GO:0071456 IEP     response to sulfur dioxide GO:0010477 IEP Subcellular Localization     plasma membrane GO:0005886 IDA     cell surface GO:0009986 ISO     extracellular exosome GO:0070062 ISO     focal adhesion GO:0005925 ISO     membrane GO:0016020 ISO     integral component of plasma membrane GO:0005887 IBA     membrane raft GO:0045121 ISO     extracellular space GO:0005615 ISO     immunological synapse GO:0001772 ISO     external side of plasma membrane GO:0009897 ISO