Gene description for Lamb2
Gene name laminin, beta 2
Gene symbol Lamb2
Other names/aliases SLAM
Species Rattus norvegicus
 Database cross references - Lamb2
ExoCarta ExoCarta_25473
Entrez Gene 25473
UniProt P15800  
 Lamb2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Lamb2
Molecular Function
    integrin binding GO:0005178 ISO
Biological Process
    axon guidance GO:0007411 ISO
    neuromuscular junction development GO:0007528 ISO
    cell morphogenesis involved in differentiation GO:0000904 ISO
    retina development in camera-type eye GO:0060041 ISO
    Schwann cell development GO:0014044 ISO
    synapse organization GO:0050808 ISO
    neuron projection development GO:0031175 ISO
    astrocyte development GO:0014002 ISO
    metanephric glomerular visceral epithelial cell development GO:0072249 ISO
    axon extension involved in regeneration GO:0048677 ISO
    cell adhesion GO:0007155 IEA
    metanephric glomerular basement membrane development GO:0072274 ISO
    visual perception GO:0007601 ISO
Subcellular Localization
    basal lamina GO:0005605 ISO
    extracellular exosome GO:0070062 ISO
    laminin complex GO:0043256 ISO
    basement membrane GO:0005604 ISO
    synapse GO:0045202 ISO
    extracellular matrix GO:0031012 ISO
    laminin-3 complex GO:0005608 ISO
 Experiment description of studies that identified Lamb2 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Lamb2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lamb2 is involved
No pathways found





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