Gene description for Psap
Gene name	prosaposin
Gene symbol	Psap
Other names/aliases	SGP-1 SGP1A
Species	Rattus norvegicus
Database cross references - Psap
ExoCarta	ExoCarta_25524
Vesiclepedia	VP_25524
Entrez Gene	25524
UniProt	P10960
Psap identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041

Gene ontology annotations for Psap

Molecular Function     G protein-coupled receptor binding GO:0001664 ISO     protease binding GO:0002020 IEA     protease binding GO:0002020 ISO     phospholipid binding GO:0005543 IEA     phospholipid binding GO:0005543 ISO     lipid antigen binding GO:0030882 ISO     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 IEA     protein homodimerization activity GO:0042803 ISO     scaffold protein binding GO:0097110 IEA     scaffold protein binding GO:0097110 ISO     ganglioside GM1 binding GO:1905573 IEA     ganglioside GM1 binding GO:1905573 ISO     ganglioside GM2 binding GO:1905574 IEA     ganglioside GM2 binding GO:1905574 ISO     ganglioside GM3 binding GO:1905575 IEA     ganglioside GM3 binding GO:1905575 ISO     ganglioside GT1b binding GO:1905576 IEA     ganglioside GT1b binding GO:1905576 ISO     ganglioside GP1c binding GO:1905577 IEA     ganglioside GP1c binding GO:1905577 ISO Biological Process     NK T cell differentiation GO:0001865 ISO     corneocyte development GO:0003335 ISO     membrane lipid metabolic process GO:0006643 ISO     glycolipid metabolic process GO:0006664 ISO     sphingolipid metabolic process GO:0006665 IEA     sphingolipid metabolic process GO:0006665 ISO     ceramide metabolic process GO:0006672 ISO     glucosylceramide metabolic process GO:0006678 ISO     galactosylceramide catabolic process GO:0006683 ISO     intracellular protein transport GO:0006886 ISO     lysosomal transport GO:0007041 IEA     lysosomal transport GO:0007041 ISO     lysosomal transport GO:0007041 ISS     adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193 IBA     adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193 IEA     adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193 ISO     sensory perception of sound GO:0007605 ISO     protein secretion GO:0009306 ISO     gene expression GO:0010467 ISO     regulation of lipid metabolic process GO:0019216 IBA     regulation of lipid metabolic process GO:0019216 IEA     regulation of lipid metabolic process GO:0019216 ISO     antigen processing and presentation GO:0019882 ISO     cerebellar Purkinje cell differentiation GO:0021702 ISO     cellular response to reactive oxygen species GO:0034614 ISO     myelination GO:0042552 ISO     regulation of MAPK cascade GO:0043408 ISO     positive regulation of MAPK cascade GO:0043410 ISO     glycolipid transport GO:0046836 NAS     developmental growth GO:0048589 ISO     nervous system process GO:0050877 ISO     neuromuscular process controlling balance GO:0050885 ISO     positive regulation of hydrolase activity GO:0051345 ISO     micturition GO:0060073 ISO     prostate gland growth GO:0060736 IBA     prostate gland growth GO:0060736 ISO     epithelial cell differentiation involved in prostate gland development GO:0060742 IBA     epithelial cell differentiation involved in prostate gland development GO:0060742 ISO     inclusion body assembly GO:0070841 ISO     cochlea development GO:0090102 ISO     walking behavior GO:0090659 ISO     cornified envelope assembly GO:1903575 ISO     positive regulation of beta-galactosidase activity GO:1903771 ISO     lysosomal protein catabolic process GO:1905146 ISO     ganglioside GM1 transport to membrane GO:1905572 IEA     ganglioside GM1 transport to membrane GO:1905572 ISO Subcellular Localization     extracellular region GO:0005576 IEA     extracellular region GO:0005576 ISO     extracellular region GO:0005576 ISS     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IEA     extracellular space GO:0005615 ISO     cytoplasm GO:0005737 ISO     lysosome GO:0005764 IBA     lysosome GO:0005764 IEA     lysosome GO:0005764 ISO     lysosome GO:0005764 ISS     late endosome GO:0005770 IEA     late endosome GO:0005770 ISO     late endosome GO:0005770 ISS     membrane GO:0016020 IEA     aggresome GO:0016235 ISO     intracellular membrane-bounded organelle GO:0043231 ISO