Gene description for Slc2a3
Gene name solute carrier family 2 (facilitated glucose transporter), member 3
Gene symbol Slc2a3
Other names/aliases GLUT3
Species Rattus norvegicus
 Database cross references - Slc2a3
ExoCarta ExoCarta_25551
Vesiclepedia VP_25551
Entrez Gene 25551
UniProt Q07647  
 Slc2a3 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
Reticulocytes 21828046    
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Slc2a3
Molecular Function
    fructose transmembrane transporter activity GO:0005353 ISO
    fructose transmembrane transporter activity GO:0005353 ISS
    galactose transmembrane transporter activity GO:0005354 ISO
    galactose transmembrane transporter activity GO:0005354 ISS
    protein binding GO:0005515 IPI
    D-glucose binding GO:0005536 IDA
    D-glucose binding GO:0005536 IEA
    D-glucose binding GO:0005536 ISO
    monosaccharide transmembrane transporter activity GO:0015145 IDA
    galactoside binding GO:0016936 IDA
    kinase binding GO:0019900 IPI
    xylose binding GO:0033222 IDA
    dehydroascorbic acid transmembrane transporter activity GO:0033300 IDA
    dehydroascorbic acid transmembrane transporter activity GO:0033300 IEA
    dehydroascorbic acid transmembrane transporter activity GO:0033300 ISO
    D-glucose transmembrane transporter activity GO:0055056 IBA
    D-glucose transmembrane transporter activity GO:0055056 IDA
    D-glucose transmembrane transporter activity GO:0055056 IEA
    D-glucose transmembrane transporter activity GO:0055056 ISO
Biological Process
    response to glucose GO:0009749 IEP
    monosaccharide transmembrane transport GO:0015749 IDA
    fructose transmembrane transport GO:0015755 ISO
    fructose transmembrane transport GO:0015755 ISS
    galactose transmembrane transport GO:0015757 ISO
    galactose transmembrane transport GO:0015757 ISS
    cerebral cortex development GO:0021987 IEP
    negative regulation of apoptotic process GO:0043066 IDA
    D-glucose import GO:0046323 IBA
    D-glucose import GO:0046323 IDA
    dehydroascorbic acid transport GO:0070837 IBA
    dehydroascorbic acid transport GO:0070837 IDA
    dehydroascorbic acid transport GO:0070837 IEA
    dehydroascorbic acid transport GO:0070837 ISO
    D-glucose import across plasma membrane GO:0098708 ISO
    transport across blood-brain barrier GO:0150104 ISO
    response to Thyroglobulin triiodothyronine GO:1904016 IEP
    D-glucose transmembrane transport GO:1904659 IDA
    D-glucose transmembrane transport GO:1904659 IEA
    D-glucose transmembrane transport GO:1904659 ISO
    D-glucose transmembrane transport GO:1904659 ISO
Subcellular Localization
    acrosomal membrane GO:0002080 IEA
    acrosomal membrane GO:0002080 ISO
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 ISO
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 ISS
    caveola GO:0005901 IDA
    membrane GO:0016020 ISO
    membrane GO:0016020 ISS
    aggresome GO:0016235 ISO
    synaptic vesicle membrane GO:0030672 IDA
    cell projection GO:0042995 IEA
    perikaryon GO:0043204 IEA
    synaptic membrane GO:0097060 IDA
    glutamatergic synapse GO:0098978 IDA
 Experiment description of studies that identified Slc2a3 in sEVs
1
Experiment ID 94
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 97
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
3
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
4
Experiment ID 99
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [QSTAR]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
5
Experiment ID 100
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [QSTAR]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Slc2a3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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