Gene description for COL24A1
Gene name collagen, type XXIV, alpha 1
Gene symbol COL24A1
Other names/aliases -
Species Homo sapiens
 Database cross references - COL24A1
ExoCarta ExoCarta_255631
Vesiclepedia VP_255631
Entrez Gene 255631
HGNC 20821
MIM 610025
UniProt Q17RW2  
 COL24A1 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for COL24A1
Molecular Function
    protein binding GO:0005515 IPI
    extracellular matrix structural constituent conferring tensile strength GO:0030020 IBA
    extracellular matrix structural constituent conferring tensile strength GO:0030020 RCA
Biological Process
    extracellular matrix organization GO:0030198 IBA
Subcellular Localization
    extracellular region GO:0005576 TAS
    collagen trimer GO:0005581 IEA
    basement membrane GO:0005604 IBA
    extracellular space GO:0005615 IBA
    endoplasmic reticulum lumen GO:0005788 TAS
    collagen-containing extracellular matrix GO:0062023 HDA
 Experiment description of studies that identified COL24A1 in sEVs
1
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for COL24A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APPBP2  
Two-hybrid Homo sapiens
2 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml



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