Gene description for Slc11a2
Gene name	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
Gene symbol	Slc11a2
Other names/aliases	Dmt1 Nramp2
Species	Rattus norvegicus
Database cross references - Slc11a2
ExoCarta	ExoCarta_25715
Entrez Gene	25715
UniProt	O54902
Slc11a2 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Slc11a2

Molecular Function     hydrogen ion transmembrane transporter activity GO:0015078 ISO     iron ion binding GO:0005506 IDA     cadmium ion transmembrane transporter activity GO:0015086 ISO     ferrous iron transmembrane transporter activity GO:0015093 ISO     cobalt ion binding GO:0050897 IDA     calcium ion transmembrane transporter activity GO:0015085 ISO     iron ion transmembrane transporter activity GO:0005381 ISO     zinc ion binding GO:0008270 IDA     manganese ion transmembrane transporter activity GO:0005384 ISO     vanadium ion transmembrane transporter activity GO:0015100 ISO     cadmium ion binding GO:0046870 ISO     chromium ion transmembrane transporter activity GO:0070835 ISO     cobalt ion transmembrane transporter activity GO:0015087 ISO     nickel cation transmembrane transporter activity GO:0015099 ISO     lead ion transmembrane transporter activity GO:0015094 ISO     zinc ion transmembrane transporter activity GO:0005385 ISO     ferrous iron uptake transmembrane transporter activity GO:0015639 ISS     nickel cation binding GO:0016151 IDA     transition metal ion transmembrane transporter activity GO:0046915 ISO     copper ion transmembrane transporter activity GO:0005375 ISO     inorganic cation transmembrane transporter activity GO:0022890 ISO     manganese ion binding GO:0030145 IDA     copper ion binding GO:0005507 IDA     solute:proton symporter activity GO:0015295 ISO Biological Process     ferrous iron import GO:0070627 ISO     transition metal ion transport GO:0000041 IDA     activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 ISO     response to cadmium ion GO:0046686 IEP     response to manganese ion GO:0010042 IMP     nickel cation transport GO:0015675 ISO     erythrocyte development GO:0048821 ISO     dendrite morphogenesis GO:0048813 ISO     copper ion import into cell GO:1902861 IMP     cellular response to oxidative stress GO:0034599 ISO     porphyrin-containing compound metabolic process GO:0006778 ISO     nickel cation transmembrane transport GO:0035444 ISO     cellular copper ion homeostasis GO:0006878 IMP     lead ion transport GO:0015692 ISO     manganese ion transport GO:0006828 ISO     response to lead ion GO:0010288 IEP     cadmium ion transmembrane transport GO:0070574 ISO     multicellular organismal iron ion homeostasis GO:0060586 ISO     proton transport GO:0015992 ISO     zinc II ion transmembrane transport GO:0071577 ISO     detection of oxygen GO:0003032 ISO     cellular response to tumor necrosis factor GO:0071356 IEP     iron ion transport GO:0006826 ISO     iron ion transmembrane transport GO:0034755 IDA     cellular response to iron ion GO:0071281 IEP     manganese ion transmembrane transport GO:0071421 ISO     ferrous iron transmembrane transport GO:1903874 ISS     learning or memory GO:0007611 ISO     copper ion transmembrane transport GO:0035434 ISO     cellular response to hypoxia GO:0071456 IEP     porphyrin-containing compound biosynthetic process GO:0006779 ISO     copper ion transport GO:0006825 ISO     vanadium ion transport GO:0015676 ISO     hydrogen ion transmembrane transport GO:1902600 ISO     heme biosynthetic process GO:0006783 ISO     response to hypoxia GO:0001666 ISO     cation transmembrane transport GO:0098655 ISO     ferrous iron transport GO:0015684 ISS     cobalt ion transport GO:0006824 ISO     response to iron ion GO:0010039 ISO Subcellular Localization     paraferritin complex GO:0070826 ISO     cell surface GO:0009986 ISO     lysosome GO:0005764 ISO     brush border GO:0005903 ISO     endomembrane system GO:0012505 ISO     apical part of cell GO:0045177 ISO     nucleus GO:0005634 ISO     late endosome membrane GO:0031902 ISO     membrane GO:0016020 ISO     retromer complex GO:0030904 ISO     trans-Golgi network GO:0005802 ISO     cytoplasm GO:0005737 ISO     late endosome GO:0005770 ISO     mitochondrial outer membrane GO:0005741 IEA     plasma membrane GO:0005886 ISO     apical plasma membrane GO:0016324 ISO     endosome GO:0005768 ISO     lysosomal membrane GO:0005765 ISO     cytoplasmic vesicle GO:0031410 ISO     integral component of plasma membrane GO:0005887 ISS     recycling endosome GO:0055037 ISO     vacuole GO:0005773 ISO     basal part of cell GO:0045178 ISO     early endosome GO:0005769 ISS     perinuclear region of cytoplasm GO:0048471 ISO     integral component of membrane GO:0016021 IDA