Gene description for Syt1
Gene name	synaptotagmin I
Gene symbol	Syt1
Other names/aliases	P65
Species	Rattus norvegicus
Database cross references - Syt1
ExoCarta	ExoCarta_25716
Entrez Gene	25716
UniProt	P21707
Syt1 identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells	20124479
Pancreatic cancer cells	20124479

Gene ontology annotations for Syt1

Molecular Function     low-density lipoprotein particle receptor binding GO:0050750 ISO     protein C-terminus binding GO:0008022 IPI     phospholipid binding GO:0005543 IDA     syntaxin-1 binding GO:0017075 IDA     calcium ion binding GO:0005509 TAS     phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IDA     calcium-dependent protein binding GO:0048306 ISO     syntaxin binding GO:0019905 IDA     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IDA     SNARE binding GO:0000149 IPI     identical protein binding GO:0042802 IPI     phosphatidylserine binding GO:0001786 IDA     calcium-dependent phospholipid binding GO:0005544 IDA     clathrin binding GO:0030276 IDA Biological Process     vesicle docking GO:0048278 IDA     response to calcium ion GO:0051592 IDA     calcium ion-dependent exocytosis GO:0017156 TAS     regulation of calcium ion-dependent exocytosis GO:0017158 IMP     positive regulation of calcium ion-dependent exocytosis GO:0045956 IDA     positive regulation of synaptic transmission GO:0050806 ISS     synaptic vesicle endocytosis GO:0048488 IBA     fast, calcium ion-dependent exocytosis of neurotransmitter GO:0098746 ISS     calcium ion-dependent exocytosis of neurotransmitter GO:0048791 IBA     detection of calcium ion GO:0005513 IDA     neurotransmitter secretion GO:0007269 ISO     brain development GO:0007420 IEP     positive regulation of dendrite extension GO:1903861 ISO     synaptic vesicle exocytosis GO:0016079 TAS     regulation of synaptic transmission, glutamatergic GO:0051966 ISS     positive regulation of vesicle fusion GO:0031340 IDA     regulation of regulated secretory pathway GO:1903305 IMP Subcellular Localization     neuron projection GO:0043005 ISO     presynaptic membrane GO:0042734 ISO     dense core granule GO:0031045 IDA     SNARE complex GO:0031201 IDA     cell GO:0005623 ISO     synaptic vesicle GO:0008021 ISO     integral component of membrane GO:0016021 IEA     cytoplasm GO:0005737 TAS     chromaffin granule membrane GO:0042584 IEA     synaptic vesicle membrane GO:0030672 TAS     excitatory synapse GO:0060076 IDA     intracellular organelle GO:0043229 IDA     secretory granule GO:0030141 ISO     cell junction GO:0030054 IEA     plasma membrane GO:0005886 IDA     terminal bouton GO:0043195 IDA