Gene description for Prkar1a
Gene name	protein kinase, cAMP-dependent, regulatory, type I, alpha
Gene symbol	Prkar1a
Other names/aliases	RIIA
Species	Rattus norvegicus
Database cross references - Prkar1a
ExoCarta	ExoCarta_25725
Vesiclepedia	VP_25725
Entrez Gene	25725
UniProt	P09456
Prkar1a identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Prkar1a

Molecular Function     cAMP-dependent protein kinase inhibitor activity GO:0004862 IBA     cAMP-dependent protein kinase inhibitor activity GO:0004862 IEA     cAMP-dependent protein kinase inhibitor activity GO:0004862 ISO     protein binding GO:0005515 IPI     cAMP-dependent protein kinase regulator activity GO:0008603 IDA     cAMP-dependent protein kinase regulator activity GO:0008603 IEA     cAMP-dependent protein kinase regulator activity GO:0008603 ISO     cAMP-dependent protein kinase regulator activity GO:0008603 TAS     protein domain specific binding GO:0019904 IEA     protein domain specific binding GO:0019904 ISO     cAMP binding GO:0030552 IBA     cAMP binding GO:0030552 IDA     cAMP binding GO:0030552 IEA     ubiquitin protein ligase binding GO:0031625 IEA     ubiquitin protein ligase binding GO:0031625 ISO     protein kinase A catalytic subunit binding GO:0034236 IBA     protein kinase A catalytic subunit binding GO:0034236 IC     protein kinase A catalytic subunit binding GO:0034236 IEA     protein kinase A catalytic subunit binding GO:0034236 ISO Biological Process     mesoderm formation GO:0001707 ISO     negative regulation of protein kinase activity GO:0006469 ISO     female meiotic nuclear division GO:0007143 IEP     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 IBA     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 ISO     heart development GO:0007507 ISO     negative regulation of gene expression GO:0010629 IEA     negative regulation of gene expression GO:0010629 ISO     positive regulation of insulin secretion GO:0032024 ISO     sarcomere organization GO:0045214 ISO     negative regulation of meiotic nuclear division GO:0045835 IEP     regulation of protein kinase activity GO:0045859 IDA     negative regulation of activated T cell proliferation GO:0046007 IEA     negative regulation of activated T cell proliferation GO:0046007 ISO     cardiac muscle cell proliferation GO:0060038 ISO     cellular response to glucagon stimulus GO:0071377 ISO     negative regulation of cAMP/PKA signal transduction GO:0141162 IEA     negative regulation of cAMP/PKA signal transduction GO:0141162 ISO     regulation of meiotic cell cycle process involved in oocyte maturation GO:1903538 ISO Subcellular Localization     immunological synapse GO:0001772 IEA     immunological synapse GO:0001772 ISO     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISO     multivesicular body GO:0005771 ISO     centrosome GO:0005813 ISO     cytosol GO:0005829 IBA     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IEA     axoneme GO:0005930 IEA     axoneme GO:0005930 ISO     cAMP-dependent protein kinase complex GO:0005952 IBA     cAMP-dependent protein kinase complex GO:0005952 IDA     cAMP-dependent protein kinase complex GO:0005952 IEA     cAMP-dependent protein kinase complex GO:0005952 ISO     nucleotide-activated protein kinase complex GO:0031588 IEA     nucleotide-activated protein kinase complex GO:0031588 ISO     neuromuscular junction GO:0031594 ISO     protein-containing complex GO:0032991 ISO     plasma membrane raft GO:0044853 IEA     plasma membrane raft GO:0044853 ISO     synapse GO:0045202 ISO     glutamatergic synapse GO:0098978 ISO     sperm head-tail coupling apparatus GO:0120212 ISO