Gene description for Mep1b
Gene name meprin 1 beta
Gene symbol Mep1b
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Mep1b
ExoCarta ExoCarta_25727
Entrez Gene 25727
UniProt P28826  
 Mep1b identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Mep1b
Molecular Function
    zinc ion binding GO:0008270 IEA
    metalloendopeptidase activity GO:0004222 IDA
Biological Process
    proteolysis GO:0006508 NAS
    toxin transport GO:1901998 ISO
    inflammatory response GO:0006954 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 ISO
 Experiment description of studies that identified Mep1b in exosomes
1
Experiment ID 192
ISEV standards
CEM
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
CD63|CD81|FLOT
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M.
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mep1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mep1b is involved
No pathways found





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