Gene description for COX2
Gene name cytochrome c oxidase II, mitochondrial
Gene symbol COX2
Other names/aliases COII
Species Rattus norvegicus
 Database cross references - COX2
ExoCarta ExoCarta_26198
Entrez Gene 26198
UniProt P00406  
 COX2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for COX2
Molecular Function
    cytochrome-c oxidase activity GO:0004129 ISS
    copper ion binding GO:0005507 IEA
    molecular_function GO:0003674 ND
Biological Process
    electron transport chain GO:0022900 IEA
    hydrogen ion transmembrane transport GO:1902600 ISS
    lactation GO:0007595 IEP
    response to cold GO:0009409 IEP
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 ISO
    mitochondrion GO:0005739 ISO
    respiratory chain complex IV GO:0045277 ISS
    extracellular exosome GO:0070062 ISO
    mitochondrial inner membrane GO:0005743 IEA
    cellular_component GO:0005575 ND
 Experiment description of studies that identified COX2 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for COX2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COX2 is involved
No pathways found





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