Gene description for ND4
Gene name NADH dehydrogenase 4, mitochondrial
Gene symbol ND4
Other names/aliases -
Species Rattus norvegicus
 Database cross references - ND4
ExoCarta ExoCarta_26201
Vesiclepedia VP_26201
Entrez Gene 26201
UniProt P05508  
 ND4 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for ND4
Molecular Function
    NADH dehydrogenase activity GO:0003954 IBA
    NADH dehydrogenase (ubiquinone) activity GO:0008137 ISO
    NADH dehydrogenase (ubiquinone) activity GO:0008137 ISS
    ubiquinone binding GO:0048039 IBA
Biological Process
    response to hypoxia GO:0001666 IEP
    in utero embryonic development GO:0001701 IEP
    mitochondrial electron transport, NADH to ubiquinone GO:0006120 ISO
    mitochondrial electron transport, NADH to ubiquinone GO:0006120 ISS
    aerobic respiration GO:0009060 IBA
    electron transport coupled proton transport GO:0015990 IBA
    cerebellum development GO:0021549 IEP
    mitochondrial respiratory chain complex I assembly GO:0032981 ISO
    mitochondrial respiratory chain complex I assembly GO:0032981 ISS
    response to nicotine GO:0035094 IEP
    response to ethanol GO:0045471 IEP
Subcellular Localization
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 ISO
    mitochondrial inner membrane GO:0005743 ISS
    respiratory chain complex I GO:0045271 IBA
    respiratory chain complex I GO:0045271 ISO
 Experiment description of studies that identified ND4 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for ND4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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