Gene description for KCNG2
Gene name potassium channel, voltage gated modifier subfamily G, member 2
Gene symbol KCNG2
Other names/aliases KCNF2
KV6.2
Species Homo sapiens
 Database cross references - KCNG2
ExoCarta ExoCarta_26251
Entrez Gene 26251
HGNC 6249
MIM 605696
UniProt Q9UJ96  
 KCNG2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for KCNG2
Molecular Function
    delayed rectifier potassium channel activity GO:0005251 TAS
Biological Process
    protein homooligomerization GO:0051260 IEA
    energy reserve metabolic process GO:0006112 TAS
    potassium ion transport GO:0006813 TAS
    regulation of insulin secretion GO:0050796 TAS
    regulation of ion transmembrane transport GO:0034765 IEA
    potassium ion transmembrane transport GO:0071805 IBA
    synaptic transmission GO:0007268 TAS
    small molecule metabolic process GO:0044281 TAS
    regulation of heart contraction GO:0008016 TAS
Subcellular Localization
    voltage-gated potassium channel complex GO:0008076 IEA
    extracellular exosome GO:0070062 IDA
    integral component of membrane GO:0016021 IBA
    plasma membrane GO:0005886 TAS
 Experiment description of studies that identified KCNG2 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for KCNG2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KCNB1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which KCNG2 is involved
PathwayEvidenceSource
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion TAS Reactome
Voltage gated Potassium channels TAS Reactome





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