Gene description for Acot7
Gene name acyl-CoA thioesterase 7
Gene symbol Acot7
Other names/aliases Bach
Species Rattus norvegicus
 Database cross references - Acot7
ExoCarta ExoCarta_26759
Entrez Gene 26759
UniProt Q64559  
 Acot7 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Acot7
Molecular Function
    fatty-acyl-CoA binding GO:0000062 ISO
    protein homodimerization activity GO:0042803 ISO
    acyl-CoA hydrolase activity GO:0047617 IDA
    carboxylic ester hydrolase activity GO:0052689 IEA
    long-chain fatty acyl-CoA binding GO:0036042 ISO
    palmitoyl-CoA hydrolase activity GO:0016290 ISO
Biological Process
    medium-chain fatty acid biosynthetic process GO:0051792 ISO
    metabolic process GO:0008152 IDA
    coenzyme A biosynthetic process GO:0015937 ISO
    medium-chain fatty-acyl-CoA catabolic process GO:0036114 ISO
    palmitic acid biosynthetic process GO:1900535 ISO
    long-chain fatty-acyl-CoA catabolic process GO:0036116 ISO
    fatty acid catabolic process GO:0009062 ISO
Subcellular Localization
    neuron projection GO:0043005 ISO
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
    extracellular exosome GO:0070062 ISO
    cytosol GO:0005829 ISO
    cell body GO:0044297 ISO
 Experiment description of studies that identified Acot7 in exosomes
1
Experiment ID 95
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Acot7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Acot7 is involved
No pathways found





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