Gene description for SNORA74A
Gene name small nucleolar RNA, H/ACA box 74A
Gene symbol SNORA74A
Other names/aliases RNU19
U19
Species Homo sapiens
 Database cross references - SNORA74A
ExoCarta ExoCarta_26821
Vesiclepedia VP_26821
Entrez Gene 26821
HGNC 10119
 SNORA74A identified in sEVs derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for SNORA74A
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    RNA processing GO:0006396 IEA
Subcellular Localization
    nucleolus GO:0005730 IEA
    box H/ACA RNP complex GO:0072588 IDA
 Experiment description of studies that identified SNORA74A in sEVs
1
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule snoRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for SNORA74A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SIRT7  
Affinity Capture-RNA Homo sapiens
2 SHMT2 6472
Affinity Capture-RNA Homo sapiens
3 NAF1  
Protein-RNA Homo sapiens
View the network image/svg+xml
 Pathways in which SNORA74A is involved
No pathways found





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