Gene description for Cadps
Gene name Ca2+-dependent secretion activator
Gene symbol Cadps
Other names/aliases AU067781
CAPS
CAPS1
mKIAA1121
Species Mus musculus
 Database cross references - Cadps
ExoCarta ExoCarta_27062
Entrez Gene 27062
UniProt Q80TJ1  
 Cadps identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cadps
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
    lipid binding GO:0008289 IEA
    protein kinase binding GO:0019901 IPI
    phosphatidylinositol-4,5-bisphosphate binding GO:0005546 ISO
    calcium ion binding GO:0005509 ISO
Biological Process
    protein transport GO:0015031 IEA
    transport GO:0006810 IEA
    vesicle organization GO:0016050 IMP
    exocytosis GO:0006887 IMP
    positive regulation of calcium ion-dependent exocytosis GO:0045956 ISO
    catecholamine secretion GO:0050432 IMP
    synaptic vesicle priming GO:0016082 IGI
Subcellular Localization
    membrane GO:0016020 IEA
    cell junction GO:0030054 IEA
    cytoplasmic vesicle GO:0031410 IDA
    synapse GO:0045202 IEA
    cell GO:0005623 IMP
 Experiment description of studies that identified Cadps in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cadps
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cadps is involved
No pathways found





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