Gene description for SRPX2
Gene name sushi-repeat containing protein, X-linked 2
Gene symbol SRPX2
Other names/aliases BPP
CBPS
PMGX
RESDX
SRPUL
Species Homo sapiens
 Database cross references - SRPX2
ExoCarta ExoCarta_27286
Entrez Gene 27286
HGNC 30668
MIM 300642
UniProt O60687  
 SRPX2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for SRPX2
Molecular Function
    receptor binding GO:0005102 IPI
    identical protein binding GO:0042802 IDA
    protein binding GO:0005515 IPI
    hepatocyte growth factor binding GO:0036458 IDA
Biological Process
    cell motility GO:0048870 IDA
    positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 ISS
    single organismal cell-cell adhesion GO:0016337 IDA
    regulation of phosphorylation GO:0042325 IDA
    positive regulation of synapse assembly GO:0051965 IDA
    vocalization behavior GO:0071625 IEA
    angiogenesis GO:0001525 IEA
Subcellular Localization
    excitatory synapse GO:0060076 ISS
    cell junction GO:0030054 IEA
    extracellular space GO:0005615 IDA
    cell surface GO:0009986 ISS
    cytoplasm GO:0005737 IDA
    synaptic membrane GO:0097060 ISS
 Experiment description of studies that identified SRPX2 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for SRPX2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SRPX2 is involved
No pathways found





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