Gene description for Akr1c13
Gene name aldo-keto reductase family 1, member C13
Gene symbol Akr1c13
Other names/aliases mKIAA4014
Species Mus musculus
 Database cross references - Akr1c13
ExoCarta ExoCarta_27384
Vesiclepedia VP_27384
Entrez Gene 27384
UniProt Q8VC28  
 Akr1c13 identified in sEVs derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Akr1c13
Molecular Function
    retinal dehydrogenase activity GO:0001758 ISO
    aldose reductase (NADPH) activity GO:0004032 IBA
    aldo-keto reductase (NADPH) activity GO:0004033 ISS
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655 ISO
    bile acid binding GO:0032052 IBA
    androsterone dehydrogenase activity GO:0047023 IBA
    androsterone dehydrogenase activity GO:0047023 ISO
    ketosteroid monooxygenase activity GO:0047086 IBA
    chlordecone reductase activity GO:0047743 ISO
Biological Process
    prostaglandin metabolic process GO:0006693 IBA
    xenobiotic metabolic process GO:0006805 TAS
    progesterone metabolic process GO:0042448 IBA
    daunorubicin metabolic process GO:0044597 IBA
    daunorubicin metabolic process GO:0044597 ISO
    doxorubicin metabolic process GO:0044598 IBA
    doxorubicin metabolic process GO:0044598 ISO
    cellular response to jasmonic acid stimulus GO:0071395 ISO
Subcellular Localization
    cytosol GO:0005829 IBA
 Experiment description of studies that identified Akr1c13 in sEVs
1
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Akr1c13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Akr1c13 is involved
No pathways found





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