Gene description for Abca3
Gene name	ATP-binding cassette, sub-family A (ABC1), member 3
Gene symbol	Abca3
Other names/aliases	1810036E22Rik ABC-C Abc3
Species	Mus musculus
Database cross references - Abca3
ExoCarta	ExoCarta_27410
Vesiclepedia	VP_27410
Entrez Gene	27410
UniProt	Q8R420
Abca3 identified in sEVs derived from the following tissue/cell type
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415

Gene ontology annotations for Abca3

Molecular Function     lipid transporter activity GO:0005319 IBA     ATP binding GO:0005524 IEA     ABC-type xenobiotic transporter activity GO:0008559 ISO     ABC-type xenobiotic transporter activity GO:0008559 ISS     ATP hydrolysis activity GO:0016887 ISO     ATP hydrolysis activity GO:0016887 ISS     ATPase-coupled transmembrane transporter activity GO:0042626 IBA     phosphatidylcholine transfer activity GO:0120019 ISO     phosphatidylcholine transfer activity GO:0120019 ISS     phosphatidylcholine flippase activity GO:0140345 ISO     phosphatidylcholine flippase activity GO:0140345 ISS Biological Process     transport GO:0006810 ISO     xenobiotic transmembrane transport GO:0006855 ISO     xenobiotic transmembrane transport GO:0006855 ISS     lipid transport GO:0006869 IBA     positive regulation of cholesterol efflux GO:0010875 ISO     positive regulation of cholesterol efflux GO:0010875 ISS     phospholipid transport GO:0015914 ISO     phospholipid transport GO:0015914 ISS     lung development GO:0030324 IMP     regulation of lipid transport GO:0032368 IMP     positive regulation of protein homooligomerization GO:0032464 IEA     positive regulation of protein homooligomerization GO:0032464 ISO     lipid translocation GO:0034204 IEA     xenobiotic transport GO:0042908 ISO     xenobiotic transport GO:0042908 ISS     surfactant homeostasis GO:0043129 IMP     phosphatidylcholine metabolic process GO:0046470 IMP     phosphatidylcholine metabolic process GO:0046470 ISO     phosphatidylcholine metabolic process GO:0046470 ISS     phosphatidylglycerol metabolic process GO:0046471 IMP     xenobiotic export from cell GO:0046618 ISO     xenobiotic export from cell GO:0046618 ISS     regulation of lipid biosynthetic process GO:0046890 IMP     response to glucocorticoid GO:0051384 IEA     phospholipid homeostasis GO:0055091 IMP     organelle assembly GO:0070925 IMP     intermembrane lipid transfer GO:0120009 IEA     regulation of phosphatidylcholine metabolic process GO:0150172 ISO     regulation of phosphatidylcholine metabolic process GO:0150172 ISS     positive regulation of phospholipid efflux GO:1902995 ISO     positive regulation of phospholipid efflux GO:1902995 ISS     positive regulation of phospholipid transport GO:2001140 ISO     positive regulation of phospholipid transport GO:2001140 ISS Subcellular Localization     lysosomal membrane GO:0005765 IEA     late endosome GO:0005770 ISO     late endosome GO:0005770 ISS     plasma membrane GO:0005886 ISO     cytoplasmic vesicle membrane GO:0030659 ISO     multivesicular body membrane GO:0032585 IEA     lamellar body GO:0042599 ISO     intracellular membrane-bounded organelle GO:0043231 IBA     alveolar lamellar body GO:0097208 ISO     lamellar body membrane GO:0097232 ISO     alveolar lamellar body membrane GO:0097233 IDA     alveolar lamellar body membrane GO:0097233 ISO