Gene description for Gpr107
Gene name G protein-coupled receptor 107
Gene symbol Gpr107
Other names/aliases 9930033D15Rik
AI790205
C530034M11
mKIAA1624
Species Mus musculus
 Database cross references - Gpr107
ExoCarta ExoCarta_277463
Vesiclepedia VP_277463
Entrez Gene 277463
UniProt Q8BUV8  
 Gpr107 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Gpr107
Molecular Function
    protein binding GO:0005515 IPI
    clathrin heavy chain binding GO:0032050 IBA
    clathrin heavy chain binding GO:0032050 IDA
Biological Process
    clathrin-dependent endocytosis GO:0072583 IBA
    clathrin-dependent endocytosis GO:0072583 IMP
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    early endosome GO:0005769 IDA
    Golgi apparatus GO:0005794 IBA
    Golgi apparatus GO:0005794 IEA
    Golgi apparatus GO:0005794 ISO
    plasma membrane GO:0005886 IEA
    membrane GO:0016020 IBA
    clathrin-coated vesicle GO:0030136 IBA
    clathrin-coated vesicle GO:0030136 IDA
 Experiment description of studies that identified Gpr107 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Gpr107
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Prex2  
Co-fractionation Mus musculus
2 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Gpr107 is involved
No pathways found





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