Gene description for SERPINA1
Gene name serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Gene symbol SERPINA1
Other names/aliases PI
Species Bos taurus
 Database cross references - SERPINA1
ExoCarta ExoCarta_280699
Vesiclepedia VP_280699
Entrez Gene 280699
UniProt P34955  
 SERPINA1 identified in sEVs derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for SERPINA1
Molecular Function
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
Biological Process
    negative regulation of endopeptidase activity GO:0010951 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified SERPINA1 in sEVs
1
Experiment ID 187
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors "Ochieng J, Pratap S, Khatua AK, Sakwe AM."
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SERPINA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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