Gene description for PPA1
Gene name pyrophosphatase (inorganic) 1
Gene symbol PPA1
Other names/aliases PP
Species Bos taurus
 Database cross references - PPA1
ExoCarta ExoCarta_280701
Entrez Gene 280701
UniProt P37980  
 PPA1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PPA1
Molecular Function
    inorganic diphosphatase activity GO:0004427 IEA
    magnesium ion binding GO:0000287 IEA
Biological Process
    phosphate-containing compound metabolic process GO:0006796 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified PPA1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PPA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PPA1 is involved
PathwayEvidenceSource
Cytosolic tRNA aminoacylation IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here