Gene description for ASS1
Gene name argininosuccinate synthase 1
Gene symbol ASS1
Other names/aliases ASS
Species Bos taurus
 Database cross references - ASS1
ExoCarta ExoCarta_280726
Entrez Gene 280726
UniProt P14568  
 ASS1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ASS1
Molecular Function
    argininosuccinate synthase activity GO:0004055 IBA
    amino acid binding GO:0016597 IEA
    poly(A) RNA binding GO:0044822 IEA
    ATP binding GO:0005524 IEA
Biological Process
    arginine biosynthetic process GO:0006526 IEA
    positive regulation of nitric oxide biosynthetic process GO:0045429 IEA
    aspartate metabolic process GO:0006531 IEA
    cellular response to laminar fluid shear stress GO:0071499 IEA
    citrulline metabolic process GO:0000052 IEA
    negative regulation of leukocyte cell-cell adhesion GO:1903038 IEA
    argininosuccinate metabolic process GO:0000053 IBA
    urea cycle GO:0000050 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified ASS1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ASS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ASS1 is involved
PathwayEvidenceSource
Urea cycle IEA Reactome





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