Gene description for CLU
Gene name	clusterin
Gene symbol	CLU
Other names/aliases	gpIII
Species	Bos taurus
Database cross references - CLU
ExoCarta	ExoCarta_280750
Entrez Gene	280750
UniProt	P17697
CLU identified in exosomes derived from the following tissue/cell type
Milk	23459212
Serum	19327352

Gene ontology annotations for CLU

Molecular Function     ATPase activity GO:0016887 ISS     ubiquitin protein ligase binding GO:0031625 ISS     misfolded protein binding GO:0051787 ISS Biological Process     negative regulation of protein homooligomerization GO:0032463 ISS     positive regulation of intrinsic apoptotic signaling pathway GO:2001244 ISS     negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage GO:1902230 ISS     positive regulation of NF-kappaB transcription factor activity GO:0051092 ISS     chaperone-mediated protein folding GO:0061077 ISS     positive regulation of apoptotic process GO:0043065 ISS     intrinsic apoptotic signaling pathway GO:0097193 ISS     positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:2000060 ISS     positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 ISS     protein stabilization GO:0050821 ISS     response to misfolded protein GO:0051788 ISS Subcellular Localization     cytosol GO:0005829 IEA     nucleus GO:0005634 IEA     extracellular space GO:0005615 ISS     spherical high-density lipoprotein particle GO:0034366 ISS     endoplasmic reticulum GO:0005783 IEA     mitochondrial membrane GO:0031966 IEA     chromaffin granule GO:0042583 IEA     extracellular matrix GO:0031012 ISS     perinuclear region of cytoplasm GO:0048471 ISS