Gene description for GPI
Gene name glucose-6-phosphate isomerase
Gene symbol GPI
Other names/aliases -
Species Bos taurus
 Database cross references - GPI
ExoCarta ExoCarta_280808
Entrez Gene 280808
UniProt Q3ZBD7  
 GPI identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GPI
Molecular Function
    cytokine activity GO:0005125 IEA
    glucose-6-phosphate isomerase activity GO:0004347 IEA
Biological Process
    glycolytic process GO:0006096 IEA
    gluconeogenesis GO:0006094 IEA
    angiogenesis GO:0001525 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    nucleoplasm GO:0005654 IEA
    cytoplasm GO:0005737 IEA
    plasma membrane GO:0005886 IEA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified GPI in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GPI
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GPI is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glycolysis IEA Reactome
TP53 Regulates Metabolic Genes IEA Reactome





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