Gene description for HBB
Gene name hemoglobin, beta
Gene symbol HBB
Other names/aliases -
Species Bos taurus
 Database cross references - HBB
ExoCarta ExoCarta_280813
Vesiclepedia VP_280813
Entrez Gene 280813
UniProt P02070  
 HBB identified in sEVs derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for HBB
Molecular Function
    peroxidase activity GO:0004601 IEA
    oxygen carrier activity GO:0005344 IEA
    oxygen binding GO:0019825 IEA
    heme binding GO:0020037 IEA
    haptoglobin binding GO:0031720 IEA
    hemoglobin alpha binding GO:0031721 IEA
    organic acid binding GO:0043177 IEA
Biological Process
    oxygen transport GO:0015671 IEA
    hydrogen peroxide catabolic process GO:0042744 IEA
Subcellular Localization
    hemoglobin complex GO:0005833 IEA
    haptoglobin-hemoglobin complex GO:0031838 IEA
    blood microparticle GO:0072562 IEA
 Experiment description of studies that identified HBB in sEVs
1
Experiment ID 187
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors "Ochieng J, Pratap S, Khatua AK, Sakwe AM."
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HBB
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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