Gene description for KNG1
Gene name kininogen 1
Gene symbol KNG1
Other names/aliases KNG
KNG2
Species Bos taurus
 Database cross references - KNG1
ExoCarta ExoCarta_280833
Entrez Gene 280833
UniProt P01045   P01044  
 KNG1 identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for KNG1
Molecular Function
    receptor binding GO:0005102 IEA
    cysteine-type endopeptidase inhibitor activity GO:0004869 IEA
Biological Process
    inflammatory response GO:0006954 IEA
    negative regulation of endopeptidase activity GO:0010951 IEA
    vasodilation GO:0042311 IEA
    negative regulation of blood coagulation GO:0030195 IEA
    positive regulation of cytosolic calcium ion concentration GO:0007204 IEA
    negative regulation of cell adhesion GO:0007162 IEA
    blood coagulation GO:0007596 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    extracellular space GO:0005615 IEA
    cytosol GO:0005829 IEA
    blood microparticle GO:0072562 IEA
 Experiment description of studies that identified KNG1 in exosomes
1
Experiment ID 187
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KNG1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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