Gene description for LPO
Gene name lactoperoxidase
Gene symbol LPO
Other names/aliases -
Species Bos taurus
 Database cross references - LPO
ExoCarta ExoCarta_280844
Entrez Gene 280844
UniProt P80025  
 LPO identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LPO
Molecular Function
    thiocyanate peroxidase activity GO:0036393 IDA
    heme binding GO:0020037 IEA
    calcium ion binding GO:0005509 IDA
Biological Process
    response to oxidative stress GO:0006979 IEA
    oxidation-reduction process GO:0055114 IEA
    detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 IEA
    thiocyanate metabolic process GO:0018969 IEA
    antibacterial humoral response GO:0019731 IDA
    hydrogen peroxide catabolic process GO:0042744 IDA
Subcellular Localization
    basolateral plasma membrane GO:0016323 IEA
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IEA
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified LPO in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LPO
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LPO is involved
No pathways found





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