Gene description for LTF
Gene name lactotransferrin
Gene symbol LTF
Other names/aliases Lf
Species Bos taurus
 Database cross references - LTF
ExoCarta ExoCarta_280846
Vesiclepedia VP_280846
Entrez Gene 280846
UniProt P24627  
 LTF identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LTF
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
    iron ion binding GO:0005506 IEA
Biological Process
    regulation of cytokine production GO:0001817 IEA
    iron ion transport GO:0006826 IEA
    antibacterial humoral response GO:0019731 IEA
    antifungal humoral response GO:0019732 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 IEA
    early endosome GO:0005769 IEA
    plasma membrane GO:0005886 IEA
    recycling endosome GO:0055037 IEA
 Experiment description of studies that identified LTF in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LTF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Traf6  
Affinity Capture-Western Mus musculus
View the network image/svg+xml



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