Gene description for CD46
Gene name CD46 molecule, complement regulatory protein
Gene symbol CD46
Other names/aliases MCP
Species Bos taurus
 Database cross references - CD46
ExoCarta ExoCarta_280851
Entrez Gene 280851
UniProt Q6VE48  
 CD46 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CD46
Biological Process
    complement activation, classical pathway GO:0006958 IEA
    single fertilization GO:0007338 IEA
    innate immune response GO:0045087 IEA
Subcellular Localization
    inner acrosomal membrane GO:0002079 IEA
    integral component of membrane GO:0016021 IEA
    cell surface GO:0009986 IEA
 Experiment description of studies that identified CD46 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD46
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CD46 is involved
No pathways found





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