Gene description for SCD
Gene name stearoyl-CoA desaturase (delta-9-desaturase)
Gene symbol SCD
Other names/aliases SCD1
Species Bos taurus
 Database cross references - SCD
ExoCarta ExoCarta_280924
Vesiclepedia VP_280924
Entrez Gene 280924
UniProt Q9TT94  
 SCD identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SCD
Molecular Function
    stearoyl-CoA 9-desaturase activity GO:0004768 IEA
    iron ion binding GO:0005506 IEA
    palmitoyl-CoA 9-desaturase activity GO:0032896 IEA
Biological Process
    unsaturated fatty acid biosynthetic process GO:0006636 IEA
    response to fatty acid GO:0070542 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified SCD in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SCD
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SCD is involved
PathwayEvidenceSource
Fatty acid metabolism IEA Reactome
Fatty acyl-CoA biosynthesis IEA Reactome
Metabolism IEA Reactome
Metabolism of lipids IEA Reactome





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