Gene description for TIE1
Gene name tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Gene symbol TIE1
Other names/aliases TIE
Species Bos taurus
 Database cross references - TIE1
ExoCarta ExoCarta_280941
Entrez Gene 280941
UniProt Q06805  
 TIE1 identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for TIE1
Molecular Function
    ATP binding GO:0005524 IEA
    transmembrane receptor protein tyrosine kinase activity GO:0004714 IEA
Biological Process
    peptidyl-tyrosine phosphorylation GO:0018108 IEA
    angiogenesis GO:0001525 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified TIE1 in exosomes
1
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TIE1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TIE1 is involved
No pathways found





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