Gene description for TTR
Gene name transthyretin
Gene symbol TTR
Other names/aliases -
Species Bos taurus
 Database cross references - TTR
ExoCarta ExoCarta_280948
Entrez Gene 280948
UniProt O46375  
 TTR identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for TTR
Molecular Function
    thyroid hormone binding GO:0070324 IEA
    identical protein binding GO:0042802 IEA
    hormone activity GO:0005179 IEA
Biological Process
    retinol metabolic process GO:0042572 IEA
    thyroid hormone transport GO:0070327 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified TTR in exosomes
1
Experiment ID 187
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TTR
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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