Gene description for TXN
Gene name thioredoxin
Gene symbol TXN
Other names/aliases -
Species Bos taurus
 Database cross references - TXN
ExoCarta ExoCarta_280950
Entrez Gene 280950
UniProt O97680  
 TXN identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TXN
Molecular Function
    poly(A) RNA binding GO:0044822 IEA
    protein disulfide oxidoreductase activity GO:0015035 IEA
    peptide disulfide oxidoreductase activity GO:0015037 IEA
Biological Process
    negative regulation of hydrogen peroxide-induced cell death GO:1903206 IEA
    positive regulation of peptidyl-serine phosphorylation GO:0033138 IEA
    oxidation-reduction process GO:0055114 ISS
    transcription, DNA-templated GO:0006351 IEA
    cell redox homeostasis GO:0045454 IEA
    response to radiation GO:0009314 ISS
    glycerol ether metabolic process GO:0006662 IEA
    positive regulation of DNA binding GO:0043388 ISS
    regulation of protein import into nucleus, translocation GO:0033158 ISS
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA
    negative regulation of protein export from nucleus GO:0046826 IEA
Subcellular Localization
    cytosol GO:0005829 IEA
    extracellular exosome GO:0070062 IEA
    nucleus GO:0005634 IEA
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified TXN in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TXN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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