Gene description for XDH
Gene name xanthine dehydrogenase
Gene symbol XDH
Other names/aliases XOR
Species Bos taurus
 Database cross references - XDH
ExoCarta ExoCarta_280960
Entrez Gene 280960
UniProt P80457  
 XDH identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for XDH
Molecular Function
    2 iron, 2 sulfur cluster binding GO:0051537 ISS
    xanthine dehydrogenase activity GO:0004854 ISS
    electron carrier activity GO:0009055 IEA
    xanthine oxidase activity GO:0004855 ISS
    flavin adenine dinucleotide binding GO:0050660 ISS
    UDP-N-acetylmuramate dehydrogenase activity GO:0008762 IEA
    molybdopterin cofactor binding GO:0043546 ISS
    iron ion binding GO:0005506 IEA
Biological Process
    xanthine catabolic process GO:0009115 ISS
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    peroxisome GO:0005777 IEA
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified XDH in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for XDH
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which XDH is involved
No pathways found





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