Gene description for AHSG
Gene name alpha-2-HS-glycoprotein
Gene symbol AHSG
Other names/aliases -
Species Bos taurus
 Database cross references - AHSG
ExoCarta ExoCarta_280988
Entrez Gene 280988
UniProt P12763  
 AHSG identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for AHSG
Molecular Function
    cysteine-type endopeptidase inhibitor activity GO:0004869 IEA
    protein binding GO:0005515 IPI
Biological Process
    negative regulation of bone mineralization GO:0030502 ISS
    positive regulation of phagocytosis GO:0050766 ISS
    acute-phase response GO:0006953 ISS
    ossification GO:0001503 IEA
    negative regulation of endopeptidase activity GO:0010951 IEA
    regulation of inflammatory response GO:0050727 ISS
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    extracellular membrane-bounded organelle GO:0065010 IDA
    blood microparticle GO:0072562 IEA
    plasma membrane GO:0005886 TAS
    vesicle GO:0031982 IDA
 Experiment description of studies that identified AHSG in exosomes
1
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AHSG
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AHSG is involved
No pathways found





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