Gene description for AMBP
Gene name alpha-1-microglobulin/bikunin precursor
Gene symbol AMBP
Other names/aliases -
Species Bos taurus
 Database cross references - AMBP
ExoCarta ExoCarta_280996
Entrez Gene 280996
UniProt P00978  
 AMBP identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for AMBP
Molecular Function
    heme binding GO:0020037 ISS
    small molecule binding GO:0036094 IEA
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
    IgA binding GO:0019862 ISS
    protein homodimerization activity GO:0042803 ISS
Biological Process
    negative regulation of endopeptidase activity GO:0010951 IEA
    protein-chromophore linkage GO:0018298 IEA
Subcellular Localization
    plasma membrane GO:0005886 ISS
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified AMBP in exosomes
1
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AMBP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AMBP is involved
No pathways found





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