Gene description for ARFGEF1
Gene name ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
Gene symbol ARFGEF1
Other names/aliases BIG1
Species Bos taurus
 Database cross references - ARFGEF1
ExoCarta ExoCarta_281022
Vesiclepedia VP_281022
Entrez Gene 281022
UniProt O46382  
 ARFGEF1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ARFGEF1
Molecular Function
    guanyl-nucleotide exchange factor activity GO:0005085 IEA
Biological Process
    regulation of ARF protein signal transduction GO:0032012 IEA
 Experiment description of studies that identified ARFGEF1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARFGEF1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ARFGEF1 is involved
No pathways found





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