Gene description for EEF2
Gene name eukaryotic translation elongation factor 2
Gene symbol EEF2
Other names/aliases EF-2
Species Bos taurus
 Database cross references - EEF2
ExoCarta ExoCarta_281138
Entrez Gene 281138
UniProt Q3SYU2  
 EEF2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EEF2
Molecular Function
    GTPase activity GO:0003924 IEA
    poly(A) RNA binding GO:0044822 IEA
    translation activator activity GO:0008494 IEA
    translation elongation factor activity GO:0003746 IEA
    protein kinase binding GO:0019901 IEA
    GTP binding GO:0005525 IEA
Biological Process
    hematopoietic progenitor cell differentiation GO:0002244 IEA
    translational elongation GO:0006414 IEA
    positive regulation of translation GO:0045727 IEA
Subcellular Localization
    aggresome GO:0016235 IEA
    polysome GO:0005844 IEA
    plasma membrane GO:0005886 IEA
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified EEF2 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EEF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which EEF2 is involved
PathwayEvidenceSource
Peptide chain elongation IEA Reactome
Synthesis of diphthamide-EEF2 IEA Reactome





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