Gene description for FASN
Gene name fatty acid synthase
Gene symbol FASN
Other names/aliases -
Species Bos taurus
 Database cross references - FASN
ExoCarta ExoCarta_281152
Entrez Gene 281152
UniProt Q71SP7  
 FASN identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FASN
Molecular Function
    enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity GO:0004319 IEA
    3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity GO:0047451 IEA
    myristoyl-[acyl-carrier-protein] hydrolase activity GO:0016295 IEA
    enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity GO:0047117 IEA
    3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316 IEA
    3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity GO:0004317 IEA
    palmitoyl-[acyl-carrier-protein] hydrolase activity GO:0016296 IEA
    [acyl-carrier-protein] S-malonyltransferase activity GO:0004314 IEA
    [acyl-carrier-protein] S-acetyltransferase activity GO:0004313 IEA
    oleoyl-[acyl-carrier-protein] hydrolase activity GO:0004320 IEA
    3-oxoacyl-[acyl-carrier-protein] synthase activity GO:0004315 IEA
    zinc ion binding GO:0008270 IEA
Biological Process
    fatty acid biosynthetic process GO:0006633 IEA
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    melanosome GO:0042470 IEA
 Experiment description of studies that identified FASN in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FASN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FASN is involved
No pathways found





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