Gene description for GDI1
Gene name GDP dissociation inhibitor 1
Gene symbol GDI1
Other names/aliases -
Species Bos taurus
 Database cross references - GDI1
ExoCarta ExoCarta_281188
Entrez Gene 281188
UniProt P21856  
 GDI1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GDI1
Molecular Function
    GTPase activator activity GO:0005096 IEA
    Rab GDP-dissociation inhibitor activity GO:0005093 ISS
Biological Process
    Rab protein signal transduction GO:0032482 IMP
    positive regulation of GTPase activity GO:0043547 IEA
    protein transport GO:0015031 IEA
    regulation of catalytic activity GO:0050790 ISS
    negative regulation of protein targeting to membrane GO:0090315 IMP
    negative regulation of axonogenesis GO:0050771 ISS
Subcellular Localization
    cytosol GO:0005829 IDA
    Golgi apparatus GO:0005794 IEA
    midbody GO:0030496 IEA
 Experiment description of studies that identified GDI1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GDI1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GDI1 is involved
PathwayEvidenceSource
Rho GTPase cycle IEA Reactome





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