Gene description for HPRT1
Gene name hypoxanthine phosphoribosyltransferase 1
Gene symbol HPRT1
Other names/aliases HGPRT
HPRT
Species Bos taurus
 Database cross references - HPRT1
ExoCarta ExoCarta_281229
Vesiclepedia VP_281229
Entrez Gene 281229
UniProt Q3SZ18  
 HPRT1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HPRT1
Molecular Function
    magnesium ion binding GO:0000287 IEA
    hypoxanthine phosphoribosyltransferase activity GO:0004422 IEA
Biological Process
    purine ribonucleoside salvage GO:0006166 IEA
    guanine salvage GO:0006178 IEA
    GMP salvage GO:0032263 IEA
    IMP salvage GO:0032264 IEA
    hypoxanthine metabolic process GO:0046100 IEA
 Experiment description of studies that identified HPRT1 in exosomes
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HPRT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HPRT1 is involved
PathwayEvidenceSource
Azathioprine ADME IEA Reactome
Drug ADME IEA Reactome
Metabolism IEA Reactome
Metabolism of nucleotides IEA Reactome
Nucleotide salvage IEA Reactome
Purine salvage IEA Reactome





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