Gene description for SDHA
Gene name succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Gene symbol SDHA
Other names/aliases -
Species Bos taurus
 Database cross references - SDHA
ExoCarta ExoCarta_281480
Entrez Gene 281480
UniProt P31039  
 SDHA identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SDHA
Molecular Function
    succinate dehydrogenase activity GO:0000104 ISS
    succinate dehydrogenase (ubiquinone) activity GO:0008177 IEA
    flavin adenine dinucleotide binding GO:0050660 IEA
Biological Process
    oxidation-reduction process GO:0055114 ISS
    electron transport chain GO:0022900 IEA
    tricarboxylic acid cycle GO:0006099 IEA
Subcellular Localization
    mitochondrion GO:0005739 ISS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749 ISS
 Experiment description of studies that identified SDHA in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SDHA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SDHA is involved
PathwayEvidenceSource
Respiratory electron transport IEA Reactome





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